3 posts
Dehydration concentrates plasma by a few percent, which is far too small to explain most ALT and AST elevations. Here is what usually causes them, how to draw a clean measurement, and how to read enzymes against your own genomic and proteomic baseline.
A working pipeline for taking Olink, SomaScan, or DIA-NN output into R: QC, missingness, normalization, and longitudinal within-person modeling of a single individual's plasma proteome.
A technical read of the MPMD/Marek Health blood panel: which assays are chosen well, which markers mislead in trained people, how to control pre-analytic noise, and where a large chemistry panel stops telling you anything new.