4 posts
A technical account of the privacy properties of consumer and clinical DNA testing: what data exists, who holds it, what re-identification attacks work, and a concrete setup for keeping your own sequence data under your control.
Pharmacogenomic panels marketed for ADHD medication selection rest on thin evidence for stimulants. Here is what the genotypes predict, which variants have real pharmacokinetic support, and how to extract them from your own sequencing data.
HIPAA compliance is a property of the entity holding your data, not of a sequencing assay. Here is what HIPAA does and does not cover for genetic data, what to read in a lab's contract instead, and how to take custody of your own FASTQ, BAM, and VCF files.
A practical comparison of Oxford Nanopore, Illumina, Element, PacBio, and Sanger for sequencing one person's genome: why we would choose nanopore long reads, what to ask a provider for, and the pipeline we would run on the output.