An essay prompted by Carolyn Bertozzi's lecture on bioorthogonal chemistry: what the reactions are, the second-order rate constants that decide what can be imaged in a living animal, and why the glycome is still a missing data layer in most molecular profiles.
What quantum mechanics says about measurement, where observer and observed are genuinely coupled in biology, and why a longitudinal personal dataset has to account for the effect of measuring on the person measured.
The Sinclair-associated biological age test is a buccal DNA methylation clock. Here is what methylation clocks measure, how noisy they are, and how to get data you can analyze yourself.